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class="content"><p><span>需求數(shù)量：</span>0</p><p><span>價(jià)格要求：</span>面議</p><p><span>所在地：</span>上海市</p><p><span>包裝要求：</span><span style="color: #f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸,煙酰胺單核苷酸</p><p><span>***更新：</span>2020-10-24 03:20:44</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="ysurov3" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海北倉化工科技有限公司</a></p><p><span>聯(lián)系人：</span>王金良</p><p><span>郵箱: </span>shbeicang@vip.126.com</p><p><span>電話: </span>18516286991</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span>http://www.shbeicang.cn</p><p><span>手機(jī): </span>021-60459206</p><p><span>地址: </span>金山大道4168號</p><p>[當(dāng)前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="ngt33s8" class="page-proshow02"><p class="title">詳細(xì)說明</p><div id="z8t3b3c" class="box"><p><p style="text-indent:25px">β-煙酰胺單核苷酸作為一種重要的有機(jī)化工原料，在化妝品、食品等行業(yè)中具有普遍的用途。煙酰胺是輔酶I(煙酰胺腺嘌呤二核苷酸)和輔酶II(煙酰胺腺嘧啶二核苷酸)的組成成分，在許多生物氧化還原反應(yīng)中起中間遞氫體的作用，對維持正常組織特別是皮膚、消化道和神經(jīng)系統(tǒng)的完整性具重要作用。在食品工業(yè)中，煙酰胺作為一種重要的食品添加劑被普遍用作糕點(diǎn)、乳制品、玉米粉等的添加劑。此外，煙酰胺還可以用作生化劑、發(fā)色劑、電鍍光亮劑、植物生長調(diào)節(jié)劑等。因此，合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸，合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸，合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸，隨著我國經(jīng)濟(jì)的迅速發(fā)展以及人民生活水平的不斷提高，對煙酰胺產(chǎn)品的需求迅速增加，研究煙酰胺系列化合物的合成具有重要的現(xiàn)實(shí)意義。β-煙酰胺單核苷酸購買需要認(rèn)準(zhǔn)官方。合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸,煙酰胺單核苷酸" src="https://tyunfile.71360.com/UploadFile/shbeicanghuagong/637326786415654296/141302.png"></div><p style="text-indent:25px">β-煙酰胺單核苷酸脫乙?；?制備煙酸乙酯核苷)：-5℃，向步驟a制得的含有煙酸乙酯三乙酰核苷的溶液中滴加乙醇鈉溶液(由17.1g，251mmol乙醇鈉溶于160mL乙醇制得)，滴加過程放熱，控制溫度在0℃以下，約0.5小時加完，滴加完畢，-5℃攪拌反應(yīng)1小時以完成反應(yīng)(TLC監(jiān)控至原料和中間體1消失)。反應(yīng)完成，滴加醋酸(15.1g，251mmol)酸化至pH為5～6，以除掉過量乙醇鈉，從而淬滅反應(yīng)。然后慢慢加入1400mL甲基叔丁基醚，-5～5℃攪拌析晶0.5小時，過濾，濾餅用甲基叔丁基醚洗滌，室溫減壓干燥，得到37.8g煙酸乙酯核苷的三氟甲磺酸鹽(含醋酸鈉)，無需除去醋酸鈉，直接用于下一步。前兩步收率加和的總收率約80％，核磁無明顯有機(jī)雜質(zhì)。哈爾濱β-煙酰胺單核苷酸廠家直銷價(jià)格煙酰胺單核苷酸是煙酰胺磷酸核糖轉(zhuǎn)移酶(Nampt)反應(yīng)的產(chǎn)物，是NAD+的關(guān)鍵前體之一。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸,煙酰胺單核苷酸" src="https://tyunfile.71360.com/UploadFile/shbeicanghuagong/637326786247109375/889767.png"></div><p style="text-indent:25px">β-煙酰胺單核苷酸在人類細(xì)胞能量的產(chǎn)生中起著重要作用，它參與細(xì)胞內(nèi)NAD (煙酰胺腺嘌呤二核苷酸，細(xì)胞能量轉(zhuǎn)換的重要輔酶)的合成。煙酰胺是維生素B3的衍生物。NAD +是一種在體內(nèi)具有多種功能的分子，主要是通過促進(jìn)稱為sirtuins的細(xì)胞信號傳導(dǎo)酶來實(shí)現(xiàn)的。這些酶對于正常功能至關(guān)重要,其中SIRT1 (有7個沉默調(diào)節(jié)蛋白)特別獨(dú)特。研究表明，熱量限制后它具有很高的活性，熱量限制本身帶來了很多好處，包括延長的跡象。毫無疑問，進(jìn)一步的測試表明，SIRT1的水平升高可以防止代謝下降和疾病。</p><p style="text-indent:25px">我公司是專業(yè)從事精細(xì)化工，有機(jī)化工，食品添加劑，醫(yī)藥原料及中間體等產(chǎn)品的研究，開發(fā)，生產(chǎn)，銷售于一體的高科技化工企業(yè)。我公司下屬工廠擁有先進(jìn)的生產(chǎn)設(shè)備和完備的生產(chǎn)車間；擁有完善的質(zhì)量保證體系和健全的質(zhì)量控制制度；廠家鄭重承諾：1，在本公司購買的β-煙酰胺單核苷酸價(jià)格相比同行業(yè)低。2，本公司全國覆蓋，產(chǎn)品出現(xiàn)問題，馬上有人員跟蹤負(fù)責(zé)，確保能及時解決客戶問題。3，本公司和各大快遞物流公司都有合作，確保合作的客戶更加快速能收貨。4，用心服務(wù)好每一個客戶是我們的心愿。β-煙酰胺單核苷酸從反應(yīng)原料看，可分為3-氰基吡啶水解法、煙酸脫水法、甲基戊二胺法。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸,煙酰胺單核苷酸" src="https://tyunfile.71360.com/UploadFile/shbeicanghuagong/637326786098613281/6911488.png"></div><p style="text-indent:25px">β-煙酰胺單核苷酸有關(guān)物質(zhì)：取本品，精密稱定，加乙醇溶解并稀釋制成每lm l中約含40mg的溶液，作為供試品溶液；精密量取適量，用乙醇分別稀釋制成每lm l中約含0. 2mg和0. lm g 的溶液，作為對照溶液（1 )和（2 ) ; 另取煙酸對照品適量，加乙醇溶解并稀釋制成每lm l中約含0 .2m g的溶液，作為對照品溶液；再取煙酸對照品和本品適量，加乙醇溶解并稀釋制成每lm l中約含煙酸0 .2m g和煙酰胺lm g 的混合溶液，作為對照溶液（3 )。照薄層色譜法（通則0502)試驗(yàn)，吸取上述5 種溶液各5M1，分別點(diǎn)于同一硅膠GF254薄層板上，以三氯甲烷-無水乙醇-水（48 : 45 ： 4 )為展開劑，展開，取出，晾干，置紫外光燈（254mn)下檢視。對照溶液（3>應(yīng)顯示兩個清晰分離的斑點(diǎn)；對照溶液（2)應(yīng)顯示一個清晰可見的斑點(diǎn)；供試品溶液如顯與對照品溶液相應(yīng)的雜質(zhì)斑點(diǎn)，其顏色與對照品溶液的主斑點(diǎn)比較，不得更深（0 .5% ) ; 如顯其他雜質(zhì)斑點(diǎn)，與對照溶液的主斑點(diǎn)比較，不得更深。煙酰胺單核苷酸，是一種自然存在的生物活性核苷酸。合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸</p><p style="text-indent:25px">防止β-煙酰胺單核苷酸泄漏物進(jìn)入下水道、地表水和地下水。合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸</p><p style="text-indent:25px">隨著年齡增加，NMN/β-煙酰胺單核苷酸和NAD+水平均呈下降趨勢，而NAD+代謝產(chǎn)物NAM呈上升趨勢。衰老過程中NAD+的下降被認(rèn)為是導(dǎo)致疾病和殘疾的主要原因，如聽力和視力喪失，認(rèn)知和運(yùn)動功能障礙，免疫缺陷，自身免疫炎癥反應(yīng)失調(diào)導(dǎo)致的關(guān)節(jié)炎、代謝障礙和心血管疾病。因此，補(bǔ)充NMN/β-煙酰胺單核苷酸提高了體內(nèi)NAD+含量，從而延緩、改善、防止衰老相關(guān)的多種表型，或年齡誘導(dǎo)的代謝紊亂、老年疾病等。作用具體有：NAD+與晝夜節(jié)律。NAD+依賴的脫乙酰酶SIRT1通過連接調(diào)節(jié)NAD+補(bǔ)救途徑的酶反饋回路和晝夜節(jié)律轉(zhuǎn)錄-翻譯反饋回路，成為晝夜節(jié)律與代謝之間的橋梁。NAD+調(diào)節(jié)生物鐘是通過SIRT1實(shí)現(xiàn)的。SIRT1將BMAL1和PER2去乙?；@和CLOCK的乙?；δ苁寝卓沟?，所以SIRT1能阻抑CLOCK- BMAL1介導(dǎo)的clock genes的轉(zhuǎn)錄。因此，NAD+通過自身水平影響SIRT1去乙?；钚?，從而反過來影響包括NAMPT在內(nèi)的一系列生物鐘相關(guān)蛋白的表達(dá)。合肥專業(yè)生產(chǎn)β-煙酰胺單核苷酸</p><p style="text-indent:25px">上海北倉化工科技有限公司主要經(jīng)營范圍是化工，擁有一支專業(yè)技術(shù)團(tuán)隊(duì)和良好的市場口碑。上海北倉化工致力于為客戶提供良好的8-羥基喹啉，β-煙酰胺單核苷酸，煙酰胺核苷，維生素C乙基醚，一切以用戶需求為中心，深受廣大客戶的歡迎。公司注重以質(zhì)量為中心，以服務(wù)為理念，秉持誠信為本的理念，打造化工良好品牌。上海北倉化工秉承“客戶為尊、服務(wù)為榮、創(chuàng)意為先、技術(shù)為實(shí)”的經(jīng)營理念，全力打造公司的重點(diǎn)競爭力。</p></p><br /><p>文章來源地址: http://m.cdcfah.com/cp/1682313.html</p></div></div></div></div></div><div id="vpbyary" class="page-right twoColRt"><div id="a2p4jya" class="box01 margin10 clearfix"><h3><a href="http://m.cdcfah.com/cp/">猜你喜歡</a></h3><div id="crtfrtf" class="recomPic likePro"><a href="http://m.cdcfah.com/cp/814588.html"><div><img src="http://tyunfile.71360.com/UpLoadFile/2019/11/1/14/637082168864691056_lgpj_5374157.jpg" alt="福建ZF配件哪家強(qiáng) 信息推薦自業(yè)物資供應(yīng)" class="vcenter" 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