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#f30;"></span></p><p><span>產(chǎn)品關(guān)鍵詞：</span>無錫煙酰胺核糖造價,煙酰胺單核苷酸</p><p><span>***更新：</span>2020-10-15 11:08:49</p><p><span id="click" >瀏覽次數(shù)：0次</span></p><a rel="nofollow" class="button">聯(lián)系我們</a></div></div><div id="fpbd7ur" class="rightbox"><h3>公司基本資料信息</h3><p style="border:0;"><a rel="nofollow">上海北倉化工科技有限公司</a></p><p><span>聯(lián)系人：</span>王金良</p><p><span>郵箱: </span>shbeicang@vip.126.com</p><p><span>電話: </span>18516286991</p><p><span>傳真: </span>021_</p><p><span>網(wǎng)址: </span>http://www.shbeicang.cn</p><p><span>手機: </span>021-60459206</p><p><span>地址: </span>金山大道4168號</p><p>[當前離線] <a rel="nofollow"> [加為商友] </a><a rel="nofollow"> [發(fā)送信件] </a></p></div></div><div id="odkmoqh" class="page-proshow02"><p class="title">詳細說明</p><div id="xhewtvc" class="box"><p><p style="text-indent:25px">β-煙酰胺單核苷酸：外觀：白色粉末；分子量：334；分子式：C11H15N2O8P；CAS ***094-61-7儲存條件：貯存在陰涼處。容器保持緊閉，儲存在干燥通風處。建議的貯存溫度： -20℃。*作為科研用途，不做其它用途，為非危險品貨物。中文別名：煙酰胺核糖一磷酸酯?，無錫煙酰胺核糖造價，煙酰胺單核苷酸?，Beta-煙酰胺單核苷酸，煙酰胺核苷酸。*用于科學研究或者工業(yè)應(yīng)用等非醫(yī)療目的，不可用于人類或動物的臨床診斷或應(yīng)對，非藥用，非食用?，F(xiàn)實中，不少商家不惜渾水摸魚，用廉價煙酸、煙酰胺冒充**NMN出售，雖然煙酸，無錫煙酰胺核糖造價、煙酰胺（NAM）理論上也能轉(zhuǎn)化為NAD+，無錫煙酰胺核糖造價，但實際效果卻難言樂觀。β-煙酰胺單核苷酸溶解性：易溶于水，幾乎不溶于**。無錫煙酰胺核糖造價</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="無錫煙酰胺核糖造價,煙酰胺單核苷酸" src="https://tyunfile.71360.com/UploadFile/shbeicanghuagong/637326786941425781/5758895.png"></div><p style="text-indent:25px">β-煙酰胺單核苷酸用途：β-Nicotinamide mononucleotide是由煙酰胺磷酸核糖基轉(zhuǎn)移酶從煙酰胺 (NAM) 和磷酸核糖焦磷酸 (PRPP) 產(chǎn)生的NAD +生物合成中的中間體。 β-煙酰胺單核苷酸作用：煙酰胺單核苷酸會轉(zhuǎn)化成體內(nèi)能量代謝必不可少的“煙酰胺腺嘌呤二核苷酸(NAD)”物質(zhì)。在小鼠試驗中，證實煙酰胺單核苷酸可活躍體內(nèi)一種叫做乙?；傅幕?，以此發(fā)揮對人體有益處的效果。NAD是人體原本可以生成的物質(zhì)，研究證實體內(nèi)的NAD含量會隨著年齡的增加而減少。β-煙酰胺單核操作處置與儲存：在有粉塵生成的地方,提供合適的排風設(shè)備。貯存在陰涼處，容器保持緊閉，儲存在干燥通風處。建議的貯存溫度： -20 °C。無錫煙酰胺核糖造價眾所周知，化工原料β-煙酰胺單核苷酸是不能直接食用的。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="無錫煙酰胺核糖造價,煙酰胺單核苷酸" src="https://tyunfile.71360.com/UploadFile/shbeicanghuagong/637326786594501953/9357235.png"></div><p style="text-indent:25px">β-煙酰胺單核苷酸制備：在100mL普通光化學反應(yīng)器中加入3-甲基吡啶18.8g(0.2mol，純度99％，含水量0.37％)、無水乙醇47g，開啟冷卻循環(huán)系統(tǒng)，開啟420nm紫光燈(功率10W)，開始以4.8g/h的流量通入亞硝酰氯以使反應(yīng)器內(nèi)液體形成較好的湍流狀態(tài)，控溫反應(yīng)溫度在15～18℃之間，反應(yīng)約3h，中控定性原料3-甲基吡啶轉(zhuǎn)化完畢。停止通入亞硝酰氯，切換至鼓入氮氣0.3h，略調(diào)小流量的同時加碳酸鈉約20g，調(diào)節(jié)pH至7.6，停止通氣，過濾析出的氯化鈉12g，濾液即為吡啶-3-甲醛肟的乙醇溶液66g，液相測定吡啶-3-甲醛肟的含量為33.64％，以3-甲基吡啶計，摩爾收率為90.95％。</p><p style="text-indent:25px">β-煙酰胺單核苷酸縮合(即制備煙酸乙酯三乙酰核苷)：1L三口瓶中加入四乙酰核糖(20g，62.8mmol)，20mL二氯甲烷，攪拌溶解，再加入煙酸乙酯(14.3g，94.3mmol)，攪拌均勻；室溫下，滴加用20mL二氯甲烷稀釋的三氟甲磺酸三甲基硅酯(TMsOTf 21g，94.3mmol)，滴加過程放熱，控制溫度在40℃以下，約0.5小時內(nèi)加完，滴加完畢，接著攪拌反應(yīng)0.5～1小時以完成反應(yīng)(TLC監(jiān)控四乙酰核糖消失)。反應(yīng)完成，反應(yīng)液冷卻至-5℃以下，滴加10mL乙醇，加完攪拌15min以破壞TMSOTf淬滅反應(yīng)，從而終止反應(yīng)。由此制得含有煙酸乙酯三乙酰核苷的溶液，該溶液無需后處理直接用于下一步。β-煙酰胺單核苷酸的容器倒空可能殘留有害物。</p><div style="width:100%;text-align: center;"><img style="max-width: 640px; max-height: 320px;" alt="無錫煙酰胺核糖造價,煙酰胺單核苷酸" src="https://tyunfile.71360.com/UploadFile/shbeicanghuagong/637326786247109375/889767.png"></div><p style="text-indent:25px">β-煙酰胺單核苷酸制備：在500ml的四口瓶中加入150ml的磷酸鹽緩沖溶液。一次性加入2g氯化鎂、10g ATP、7g核糖、10g煙酰胺，在35℃保溫攪拌。檢測反應(yīng)體系的pH值，并用10％Na2CO3溶液調(diào)pH＝8.0，再加入1gRK酶粉、2gNAMPT酶粉，攪拌溶解。于37℃下，200rpm攪拌反應(yīng)，利用液相色譜-質(zhì)譜聯(lián)用監(jiān)測反應(yīng)的轉(zhuǎn)化率，經(jīng)過6小時反應(yīng)后，檢測ATP已經(jīng)消耗完畢，停止反應(yīng)。通過進一步的過濾，HZ-818型大孔樹脂吸附，凍干，乙醇和水重結(jié)晶即可獲得β-煙酰胺單核苷酸-煙酰胺單核苷酸NMN，收率70％。β-煙酰胺單核苷酸遠離火種、熱源，工作場所嚴禁吸煙。無錫煙酰胺核糖造價</p><p style="text-indent:25px">β-煙酰胺單核苷酸-煙酰胺單核苷酸又叫β-煙酰胺單核苷酸(NMN)，是輔酶I的合成底物。無錫煙酰胺核糖造價</p><p style="text-indent:25px">通過Nad+的補充達到修復(fù)DNA的目的,科學給出的答案是主要依靠這4種前體,分別為煙酸、色氨酸和煙酰胺以及NR/煙酰胺單核苷酸,但**者具備副作用。煙酸補充Nad+:煙酰胺通過合成形成維生素PP,水溶性維生素,是維生素B族成員,人體必需維生素之一,尤其肝臟,奶類,蛋類,蔬菜,酵母,蘑菇,花莖甘藍,全谷及一些水果這些**食品,缺點是在腎功能不正常時會產(chǎn)生不良反應(yīng);色氨酸補充Nad+:這里的一大阻礙是,對于缺乏維生素B1、B2、B6的群體,無法實現(xiàn)經(jīng)色氨酸合成煙酸的過程,即便實現(xiàn),轉(zhuǎn)化率卻極低。60:1,這是哺乳動物轉(zhuǎn)化的比例值。富含蛋白質(zhì)的食物,如肉類、魚類、牛奶、香蕉等**食品一個成年人每日需要的攝取量將達到100到500毫克之間;β-煙酰胺單核苷酸補充Nad+:它的毒副作用主要體現(xiàn)在其阻抑Sirtuins。無錫煙酰胺核糖造價</p><p style="text-indent:25px">上海北倉化工科技有限公司致力于化工，是一家生產(chǎn)型的公司。公司業(yè)務(wù)涵蓋8-羥基喹啉，β-煙酰胺單核苷酸，煙酰胺核苷，維生素C乙基醚等，價格合理，品質(zhì)有保證。公司注重以質(zhì)量為中心，以服務(wù)為理念，秉持誠信為本的理念，打造化工良好品牌。上海北倉化工秉承“客戶為尊、服務(wù)為榮、創(chuàng)意為先、技術(shù)為實”的經(jīng)營理念，全力打造公司的重點競爭力。</p></p><br /><p>文章來源地址: http://m.cdcfah.com/cp/1565426.html</p></div></div></div></div></div><div id="kubtq3r" class="page-right twoColRt"><div id="3hegdam" class="box01 margin10 clearfix"><h3><a href="http://m.cdcfah.com/cp/">猜你喜歡</a></h3><div id="8z8o73a" class="recomPic likePro"><a 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